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Type 2 Diabetes Revielle (Re-Vuh-Lee)

 I went to the doctor, she gave me this sample of  
an injectable drug that you  inject into your belly fat.  
 
It lasts one week, between the next shot.  
I hate shots, I put off trying the sample for  
about a week,
but I got tired of poking my finger  
and getting a high reading of 300, even though  
I tried to do the dieting technique.  
 
After five days,
my irritableness, my aching legs,
lack of ability to move fast,  
all these things are fading away.
 
I have been reading on the web,  
To find out how this drug works.  
 
It is only 2 mg,
which is really a tiny amount to be  
able to work for a whole week.  
I mean, by comparison,  
my metformin pill is 1000 mg,
and I am supposed to take that twice a day.  
 
If you ever have been diabetic,
you probably got the mini-lecture  
that your pancreas is not responding to food intake,
it is not releasing insulin  to deal with the food you ate.  
 
I will leave the explanation of insulin for another day.
let us just say that the pancreas needs to release insulin
as the sugar level in the blood rises,  
and the insulin signals the rest of the body to deal with the sugar.  
 
So they tell the diabetic patient that their pancreas is not responding well,
and bla bla bla.  
They dont tell you WHY your pancreas is not working as it should.  
 
Well, it turns out there is a missing part to this story.
When a normal person eats food,  
and the food gets to the intestines,  
your intestines,  
or rather a few special cells in the intestines,  
release a tiny quantity of a hormone that floats around the blood stream,  
and when this hormone, (GLP-1),  
touches the cells inside the pancreas,  
it 'wakes the pancreas up'    
Kind of like that military wake up song,
called Reveille (Re-Vuh-Lee)  
 
Without this 'wakeup' hormone,
your pancreas actually checks out,
goes to sleep, goes dormant,  
when no food is in the intestines.    

Kind of like when you were a kid,
going into your moms bedroom when she was sleeping to ask her for a drink of water. She will get it, but it will take a while.    
 
A type two diabetic can actually have a perfectly normal pancreas,  
able to excrete insulin, it is just not being woken up.  
 
That is the missing piece of the puzzle.    
The 'smoke signal' from the intestines, in a type II diabetic,  
is not happening.    
It is not floating around your bloodstream.    
It is not there to tell your pancreas to wake up.  
It is not there to float thru your brain,
to tell you that there is food in your guts.  
 
Lacking this tiny amount of the glp-1  hormone,  
your brain does not get the signal that it has food in your belly,  
AND your pancreas is still snoring away,  
even though your bloodstream is filling up with
more and more sugar from the food you ate.  

(The food leaving the intestines, and entering the rich network of blood vessels that surround the intestines, to receive the processed food molecules from what you have eaten)  
 
This new drug 'mimics' this GLP-1 smoke signal intestinal hormone.    
In the case of the slo-release-one-week-between-dose injection,  
it releases microgram quantities of the hormone over the course of the whole week, until your next shot.  
It signals to your pancreas that there is ALWAYS food in your intestine,
and so your pancreas always is on duty,
actively keeping your  blood sugar under control.  
 
This new 'mimic' drug,
also is constantly floating around in your blood stream,
and there are also sensors in your brain for this hormone mimic drug,
so you always feel content, in terms of food.  

In the comments people who have tried the drug have left on various forums,  
one wrote that they actually forgot to eat a meal,
as they didn't feel hungry.  
 
This new drug,
also is the ONLY  drug out there,
which has shown evidence that it actually
reduces or eliminates diabetes in some percentage of patients.  

Yeah. It lets people lose weight, reduce their appetite,
plus gives them normal sugar levels,
and after some time, their intestines repair themselves,
and their intestines start making their own natural GLP-1 hormone once again.
   
So if you are interested in finding out about this new drug,  
here are some keywords for a google search:  
 
" GLP-1 mimetics , wikipedia"  
 
This should bring you to a wikipedia article that
 talks about all the drugs that mimic the intestine smoke signal hormone.  

The one I tried is the one that lasts for one week,
and was approved in 2012.  Its trade name  
starts with a B.  B as in Bydureon.
 
Thats right. 2012.  That is recent.  
Doctors who prescribe meds, along with the landscape of diabetics drugs
have been going on for over 50 years.  
You and your friend with Diabetes II,
 may need to learn about this new drug by themselves,
and even bring some of the literature they read to their doctor
to ask if they can have it.  
If your doctor says no,
then maybe you need to try a new doctor.

 For what this drug is doing to me,
it is like waking from a long sleep.  
 
 
*(with a high sugar in your blood, your are much more  
easily attacked by bacteria, fungi, etc, because the sugar is food to them)  
 
PS: This missing piece of the story also suggests an explanation of the type II diabetics  
experience: It is that GLP-1 hormone smoke signal that tells your brain that it has food in the intestines.   Without that signal, you feel like you need to eat some more.  Then without that signal, the pancreas is no secreting insulin, and sugar levels rise in the blood. The high sugar in the blood makes you prone to infections, and the immune system goes into overdrive fighting infections.  In the battle with all the white blood cells on patrol, some of the body's own parts gets attacked by accident, such as arthritis, where the joints surfaces gets attacked, and probably lets say your intestine smoke signal cells get hit by your own immune system.    
 
That would 'lock in' the diabetes:  
(High sugar causes the immune system to accidentally attack glp-1 producing intestinal cells.  
Lack of glp-1 signal from intestines makes you feel hungry, and with the pancreas not woken up, your shugar stays high)  
 
 
 
Written by rabbitquest
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