Corona Virus ( Covid-19 )
Rep. Mark Green (R-TN) : The old reliable Malaria drug chloroquine, the newer version hydroxychloroquine has shown really good, three studies, one in Australia, one in China and now one in France mixed with azithromycin, just the old Z-Pac that we take for bronchitis, has had 100%. It cleared the virus, in some cases in three days, that cocktail in every one of the patients in that study… It’s very promising, 100% of the virus gone in six days!
Another sunny day today in my world.
Another sunny day today in my world.
Today's Worldometer
Coronavirus Cases: 247,595 ( + 47,497 )
Deaths: 10,064 ( + 2,054 )
Recovered: 88,522 82,813 ( + 5,079 )
US Cases: 14,366 ( + 7,842 )
Deaths: 217 116 ( + 101 )
Recovered: 125 106 ( + 19 )
Joe do you have a link for that? I would like to read it myself.
Fact check: Trump wrongly claims FDA 'approved' drug chloroquine to treat the coronavirus
Washington (CNN)President Donald Trump claimed during a White House briefing on Thursday that the Food and Drug Administration had approved the "very powerful" drug chloroquine to treat coronavirus.
"It's shown very encouraging -- very, very encouraging early results. And we're going to be able to make that drug available almost immediately. And that's where the FDA has been so great. They -- they've gone through the approval process; it's been approved. And they did it -- they took it down from many, many months to immediate. So we're going to be able to make that drug available by prescription or states," Trump said.
He added: "Normally the FDA would take a long time to approve something like that, and it's -- it was approved very, very quickly and it's now approved, by prescription."
Chloroquine is used to treat malaria, lupus and rheumatoid arthritis.
Facts First: Chloroquine has not been approved by the FDA to treat the coronavirus -- and nor has any other drug, the FDA made clear in a post-briefing statement that said "there are no FDA-approved therapeutics or drugs to treat, cure or prevent COVID-19." Because chloroquine has been approved for other purposes, doctors are legally allowed to prescribe it for the unapproved or "off-label" use of treating the coronavirus if they want. But its safety and effectiveness has not been proven with regard to the coronavirus. FDA Commissioner Dr. Stephen Hahn, speaking after Trump at the briefing, said that chloroquine would be tested through a "large, pragmatic clinical trial" with coronavirus patients.
The FDA said in the statement that it is working with government and academic entities that are investigating whether chloroquine can be used "to treat patients with mild-to-moderate COVID-19 to potentially reduce the duration of symptoms, as well as viral shedding, which can help prevent the spread of disease."
Studies are underway. Hahn emphasized that this study process is necessary even though the coronavirus situation is urgent.
"We also must ensure these products are effective; otherwise we risk treating patients with a product that might not work when they could have pursued other, more appropriate, treatments," Hahn said in the statement.
Pharmaceutical company Bayer ( AKA Monsanto ) announced on Thursday that it is donating 3 million tablets of its chloroquine phosphate drug, sold under the name Resochin, to the US government.
"New data from initial preclinical and evolving clinical research conducted in China, while limited, shows potential for the use of Resochin in treating patients with COVID-19 infection,"Bayer Monsanto said in a statement.
[. . .]
https://www.cnn.com/2020/03/19/politics/fact-check-chloroquine-trump-fda/index.html
Here's an interview with a Dr. Agus about Hydroxychloroquine.
https://www.cbsnews.com/news/coronavirus-there-is-hope-two-drugs-that-could-help-patients-fight-back/
Coronavirus Cases: 247,595 ( + 47,497 )
Deaths: 10,064 ( + 2,054 )
Recovered: 88,522 82,813 ( + 5,079 )
US Cases: 14,366 ( + 7,842 )
Deaths: 217 116 ( + 101 )
Recovered: 125 106 ( + 19 )
Joe do you have a link for that? I would like to read it myself.
Fact check: Trump wrongly claims FDA 'approved' drug chloroquine to treat the coronavirus
Washington (CNN)President Donald Trump claimed during a White House briefing on Thursday that the Food and Drug Administration had approved the "very powerful" drug chloroquine to treat coronavirus.
"It's shown very encouraging -- very, very encouraging early results. And we're going to be able to make that drug available almost immediately. And that's where the FDA has been so great. They -- they've gone through the approval process; it's been approved. And they did it -- they took it down from many, many months to immediate. So we're going to be able to make that drug available by prescription or states," Trump said.
He added: "Normally the FDA would take a long time to approve something like that, and it's -- it was approved very, very quickly and it's now approved, by prescription."
Chloroquine is used to treat malaria, lupus and rheumatoid arthritis.
Facts First: Chloroquine has not been approved by the FDA to treat the coronavirus -- and nor has any other drug, the FDA made clear in a post-briefing statement that said "there are no FDA-approved therapeutics or drugs to treat, cure or prevent COVID-19." Because chloroquine has been approved for other purposes, doctors are legally allowed to prescribe it for the unapproved or "off-label" use of treating the coronavirus if they want. But its safety and effectiveness has not been proven with regard to the coronavirus. FDA Commissioner Dr. Stephen Hahn, speaking after Trump at the briefing, said that chloroquine would be tested through a "large, pragmatic clinical trial" with coronavirus patients.
The FDA said in the statement that it is working with government and academic entities that are investigating whether chloroquine can be used "to treat patients with mild-to-moderate COVID-19 to potentially reduce the duration of symptoms, as well as viral shedding, which can help prevent the spread of disease."
Studies are underway. Hahn emphasized that this study process is necessary even though the coronavirus situation is urgent.
"We also must ensure these products are effective; otherwise we risk treating patients with a product that might not work when they could have pursued other, more appropriate, treatments," Hahn said in the statement.
Pharmaceutical company Bayer ( AKA Monsanto ) announced on Thursday that it is donating 3 million tablets of its chloroquine phosphate drug, sold under the name Resochin, to the US government.
"New data from initial preclinical and evolving clinical research conducted in China, while limited, shows potential for the use of Resochin in treating patients with COVID-19 infection,"
[. . .]
https://www.cnn.com/2020/03/19/politics/fact-check-chloroquine-trump-fda/index.html
Here's an interview with a Dr. Agus about Hydroxychloroquine.
https://www.cbsnews.com/news/coronavirus-there-is-hope-two-drugs-that-could-help-patients-fight-back/
Anonymous
<< post removed >>
Coronavirus: US home repossessions suspended amid crisis
https://www.bbc.com/news/world-us-canada-51954557?fbclid=IwAR2msEgGUtqtRUpWzZQwfVW1_wDWLp7XeMENIACogijZQzFgKcUjLsvWzRI
So that's homes, power, internet. . .which should alleviate the stress level. This is America coming together.
https://www.bbc.com/news/world-us-canada-51954557?fbclid=IwAR2msEgGUtqtRUpWzZQwfVW1_wDWLp7XeMENIACogijZQzFgKcUjLsvWzRI
So that's homes, power, internet. . .which should alleviate the stress level. This is America coming together.
Here’s the latest communique from the Red Cross about the state of the blood supply:
Dear Transfusion Services Partners,
Every day the American Red Cross works to protect patient care through an adequate and available blood supply. However, amid the nation’s powerful response to the novel coronavirus (COVID-19) pandemic, blood providers are challenged to replace both eligible donors and the needed facilities to operate productive blood drives. Red Cross has had more than 4,600 blood drives canceled, resulting in 143,600 fewer units. Consequently, the Red Cross has launched a nationwide media appeal to generate public awareness of the critical need for continued blood donations throughout the pandemic and that blood is essential to health care. Donating blood is safe and necessary. Please encourage the continuation of blood drives and donations in your hospital and community.
As we work to build new blood supplies, we are also aggressive in securing those products already on the shelf. We appreciate your rapid response to our request for proactive conservation to safeguard limited inventories. Through our combined efforts, the rate of decline of the red blood cell supply has slowed. However, we have yet to realize the full impact of the pandemic response and government ordered quarantines. Our inventory projections indicate red blood cells will be severely constrained by next week. We must remain vigilant.
With red blood cell supplies expected to worsen quickly, we are discontinuing stock rotations and auto-return/replenish ordering. We recommend hospitals retain products in-house through expiration as our ability to restock with longer dated products will be greatly diminished. Place new orders only as inventory is used or expired.
Several hospitals and health systems around the country have already chosen to cancel elective surgeries. If you have not done so, we strongly recommend hospitals postpone or cancel elective surgical procedures at this time.
Also if you want a medical perspective on Corona , you can sign up for this webinar series :
https://www.labroots.com/ms/virtual-event/coronavirus
Dear Transfusion Services Partners,
Every day the American Red Cross works to protect patient care through an adequate and available blood supply. However, amid the nation’s powerful response to the novel coronavirus (COVID-19) pandemic, blood providers are challenged to replace both eligible donors and the needed facilities to operate productive blood drives. Red Cross has had more than 4,600 blood drives canceled, resulting in 143,600 fewer units. Consequently, the Red Cross has launched a nationwide media appeal to generate public awareness of the critical need for continued blood donations throughout the pandemic and that blood is essential to health care. Donating blood is safe and necessary. Please encourage the continuation of blood drives and donations in your hospital and community.
As we work to build new blood supplies, we are also aggressive in securing those products already on the shelf. We appreciate your rapid response to our request for proactive conservation to safeguard limited inventories. Through our combined efforts, the rate of decline of the red blood cell supply has slowed. However, we have yet to realize the full impact of the pandemic response and government ordered quarantines. Our inventory projections indicate red blood cells will be severely constrained by next week. We must remain vigilant.
With red blood cell supplies expected to worsen quickly, we are discontinuing stock rotations and auto-return/replenish ordering. We recommend hospitals retain products in-house through expiration as our ability to restock with longer dated products will be greatly diminished. Place new orders only as inventory is used or expired.
Several hospitals and health systems around the country have already chosen to cancel elective surgeries. If you have not done so, we strongly recommend hospitals postpone or cancel elective surgical procedures at this time.
Also if you want a medical perspective on Corona , you can sign up for this webinar series :
https://www.labroots.com/ms/virtual-event/coronavirus
Thank you, MadameL. We do hope you are taking care of yourself and getting plenty of rest! I wish I could give blood, but I can't right now.
The latest: Hell has frozen over.
U.S. Extends Individual Tax Filing Deadline from April 15 to July 15
Tax preparers and lawmakers in both parties urged that the traditional April 15 deadline be moved due to the coronavirus
WASHINGTON—The U.S. is extending the April 15 tax-filing deadline to July 15, giving people more time to prepare and pay their taxes during the coronavirus outbreak, Treasury Secretary Steven Mnuchin said Friday.
“All taxpayers and businesses will have this additional time to file and make payments without interest or penalties."
https://www.wsj.com/articles/u-s-extends-individual-tax-filing-deadline-to-july-15-11584713903?mod=e2fb&fbclid=IwAR3Lb2_Poh228pEboggh2kB9pFJuV8O8DrnWwyoFuH_UpbuyWIg0IgqLjqg
The latest: Hell has frozen over.
U.S. Extends Individual Tax Filing Deadline from April 15 to July 15
Tax preparers and lawmakers in both parties urged that the traditional April 15 deadline be moved due to the coronavirus
WASHINGTON—The U.S. is extending the April 15 tax-filing deadline to July 15, giving people more time to prepare and pay their taxes during the coronavirus outbreak, Treasury Secretary Steven Mnuchin said Friday.
“All taxpayers and businesses will have this additional time to file and make payments without interest or penalties."
https://www.wsj.com/articles/u-s-extends-individual-tax-filing-deadline-to-july-15-11584713903?mod=e2fb&fbclid=IwAR3Lb2_Poh228pEboggh2kB9pFJuV8O8DrnWwyoFuH_UpbuyWIg0IgqLjqg
Ahavati said:Thank you, MadameL. We do hope you are taking care of yourself and getting plenty of rest! I wish I could give blood, but I can't right now.
Doing my best ! Unfortunately I can’t donate either—I got booted off the marrow and blood donor lists , for life, 11 years ago when I had cancer. But at least I can give my time as a lab tech .
Doing my best ! Unfortunately I can’t donate either—I got booted off the marrow and blood donor lists , for life, 11 years ago when I had cancer. But at least I can give my time as a lab tech .
MadameLavender said:
Doing my best ! Unfortunately I can’t donate either—I got booted off the marrow and blood donor lists , for life, 11 years ago when I had cancer. But at least I can give my time as a lab tech .
We all do what we can. This is for YOU ( and all the other healthcare workers ) - from my porch!
Spain thanks medical workers during COVID-19 crisis
https://www.facebook.com/KHQLocalNews/videos/246378256523985/UzpfSTEyNzEyNjIyMTc6MTAyMTY4ODEzNjQwNDc2NTI/
Doing my best ! Unfortunately I can’t donate either—I got booted off the marrow and blood donor lists , for life, 11 years ago when I had cancer. But at least I can give my time as a lab tech .
We all do what we can. This is for YOU ( and all the other healthcare workers ) - from my porch!
Spain thanks medical workers during COVID-19 crisis
https://www.facebook.com/KHQLocalNews/videos/246378256523985/UzpfSTEyNzEyNjIyMTc6MTAyMTY4ODEzNjQwNDc2NTI/
Remdesivir has been recently recognized as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5) infection in cultured cells, mice and nonhuman primate (NHP) models. It is currently under clinical development for the treatment of Ebola virus infection.6 Remdesivir is an adenosine analogue, which incorporates into nascent viral RNA chains and results in pre-mature termination...Our preliminary data (Supplementary information, Fig. S2) showed that remdesivir also inhibited virus infection efficiently in a human cell line (human liver cancer Huh-7 cells), which is sensitive to 2019-nCoV.
Chloroquine, a widely-used anti-malarial and autoimmune disease drug, has recently been reported as a potential broad-spectrum antiviral drug.8,9 Chloroquine is known to block virus infection by increasing endosomal pH required for virus/cell fusion, as well as interfering with the glycosylation of cellular receptors of SARS-CoV.
Our findings reveal that remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro. Since these compounds have been used in human patients with a safety track record and shown to be effective against various ailments, we suggest that they should be assessed in human patients suffering from the novel coronavirus disease. @ https://www.nature.com/articles/s41422-020-0282-0
Beautiful, sunny day here, and everything is green with pollen!
Chloroquine, a widely-used anti-malarial and autoimmune disease drug, has recently been reported as a potential broad-spectrum antiviral drug.8,9 Chloroquine is known to block virus infection by increasing endosomal pH required for virus/cell fusion, as well as interfering with the glycosylation of cellular receptors of SARS-CoV.
Our findings reveal that remdesivir and chloroquine are highly effective in the control of 2019-nCoV infection in vitro. Since these compounds have been used in human patients with a safety track record and shown to be effective against various ailments, we suggest that they should be assessed in human patients suffering from the novel coronavirus disease. @ https://www.nature.com/articles/s41422-020-0282-0
Beautiful, sunny day here, and everything is green with pollen!
12 days ago the US coronavirus mortality rate was 4.06
Today the mortality rate is down to 1.25%!
4.06% March 8 (22 deaths of 541 cases)
3.69% March 9 (26 of 704)
3.01% March 10 (30 of 994)
2.95% March 11 (38 of 1,295)
2.52% March 12 (42 of 1,695)
2.27% March 13 (49 of 2,247)
1.93% March 14 (57 of 2,954)
1.84% March 15 (68 of 3,680)
1.6% March 17 (116 of 7,301)
1.4% March 19 (161 of 11,329)
1.25% March 20 (237 of 18,845)
So, more testing leads to spike cases. Deaths lag.
34 times as many cases March 8th to March 20th. Only 10 times as many deaths. Yes, 237 deaths matter but there were 22,000 flu deaths last season. Perspective matters too.
Today the mortality rate is down to 1.25%!
4.06% March 8 (22 deaths of 541 cases)
3.69% March 9 (26 of 704)
3.01% March 10 (30 of 994)
2.95% March 11 (38 of 1,295)
2.52% March 12 (42 of 1,695)
2.27% March 13 (49 of 2,247)
1.93% March 14 (57 of 2,954)
1.84% March 15 (68 of 3,680)
1.6% March 17 (116 of 7,301)
1.4% March 19 (161 of 11,329)
1.25% March 20 (237 of 18,845)
So, more testing leads to spike cases. Deaths lag.
34 times as many cases March 8th to March 20th. Only 10 times as many deaths. Yes, 237 deaths matter but there were 22,000 flu deaths last season. Perspective matters too.
Total cases per day = 1.024 x e^(0.145 x number of days from case 1)
Formula matches to R^2 value of 0.9148. Formula derived by myself, for amusement, based on data available.
That’s an exponential growth curve.
That means the numbers of cases starts slow/low and climbs very very quickly, until intervention efforts begin to flatten curve.
Flue death rate runs well under <1%.
Current worldwide deaths rate is above 3.5%, weighted toward the elderly and immunocompromised, but is still deadly to a percentage of well or younger people that is higher than common flus.
This is a time to think not, “what can I do to protect myself”, but rather “what can I do to protect others”.
Side comment. The US healthcare system will deliver a mortality rate higher than the worldwide average, due to its poor preparedness and low accessibility by at-risk groups.
Nations doing particularly well are ones that acted early and have geographical borders. Go New Zealand!
Written from my boat, lying off a remote island, and “working from home”, managing the demob of several hundred people out of the Pacific region.
Formula matches to R^2 value of 0.9148. Formula derived by myself, for amusement, based on data available.
That’s an exponential growth curve.
That means the numbers of cases starts slow/low and climbs very very quickly, until intervention efforts begin to flatten curve.
Flue death rate runs well under <1%.
Current worldwide deaths rate is above 3.5%, weighted toward the elderly and immunocompromised, but is still deadly to a percentage of well or younger people that is higher than common flus.
This is a time to think not, “what can I do to protect myself”, but rather “what can I do to protect others”.
Side comment. The US healthcare system will deliver a mortality rate higher than the worldwide average, due to its poor preparedness and low accessibility by at-risk groups.
Nations doing particularly well are ones that acted early and have geographical borders. Go New Zealand!
Written from my boat, lying off a remote island, and “working from home”, managing the demob of several hundred people out of the Pacific region.
